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The paradoxical (nonprespecified) finding of a greater reduction of LDL with ezetimibe associated with carotid IMT progression was highlighted prominently in the ...ENHANCE trial update: no beneficial effects on CA IMT from ezetimibe. The much-awaited results of the “Ezetimibe and Simvastatin in Hypercholesterolemia …Efficacy and Safety of Coadministration of Ezetimibe and Simvastatin in Adolescents With ... Further work in the context of optimized lipid-lowering therapy, using carotid IMT ...Nov 25, 2007 · Sinvastatin (Zocor) has been combined with ezetimibe (Zetia) to yield combination ... primary outcomes of carotid intima-media thickness and femoral artery (IMT).Furthermore, these studies suggest that reductions in the rates of atherosclerosis progression can be deduced through reduction in rates of IMT progression. Ezetimibe …In the publication, the authors addressed the premise that the lack of a difference in change of mean CA IMT between ezetimibe/simvastatin and simvastatin despite …Mar 30, 2008 · In the publication, the authors addressed the premise that the lack of a difference in change of mean CA IMT between ezetimibe/simvastatin and …The differences in mean change in the intima-media thickness (IMT) between the Zocor (simvastatin) and Vytorin (ezetimibe and simvastatin) group was 0.006 …... study is to evaluate the effects of long-term combined Ezetimibe/Simvastatin (EZE/SIMVA) therapy (30 months) on the lipidic pattern, inflammatory markers, and carotid IMT ...Secondary Outcome Measures: Proportion of subjects with a reduction in ultrasound-determined average carotid artery IMT between baseline and endpoint.